936716-47-1

Upstream product

• 79099-07-3 N-tert-butyloxycarbonylpiperidin-4-one 
• 99578-85-5 diethyl [[2-(trifluoromethyl)phenyl]methyl]phosphonate 

Downstream Products

• 336182-27-5 1-piperidinecarboxylic acid, 4-(2-trifluoromethylphenylmethyl),-1,1-dimethylethyl ester 
• 1057314-62-1 4-[2-(trifluoromethyl)benzyl]piperidinium chloride 

Relevant academic research and scientific papers

PYRIDAZINONES AND METHODS OF USE THEREOF

Disclosed are compounds according to Formula (A), and related tautomers and pharmaceutical compositions. Also disclosed are therapeutic methods, e.g., of treating kidney diseases, using the compounds of Formula (A).

HETEROAROMATIC COMPOUNDS AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE

Heteroaromatic compounds of structural formula (I) are selective inhibitors of stearoyl-coenzyme A delta-9 desaturase (SCD1) relative to other known stearoyl-coenzyme A desaturases. The compounds of the present invention are useful for the prevention and

AZACYCLOHEXANE DERIVATIVES AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE

Azacyclohexane derivatives of structural formula I are selective inhibitors of stearoyl-coenzyme A delta-9 desaturase (SCD1) relative to other known stearoyl-coenzyme A desaturases. The compounds of the present invention are useful for the prevention and treatment of conditions related to abnormal lipid synthesis and metabolism, including cardiovascular disease, such as atherosclerosis; obesity; diabetes; neurological disease; metabolic syndrome; insulin resistance; and liver steatosis.