Cas 936727-80-9,(R)-[1-(4-bromobenzenesulfonyl)pyrrolidin-2-yl]methanol

936727-80-9

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Basic information

Product Name: (R)-[1-(4-bromobenzenesulfonyl)pyrrolidin-2-yl]methanol
Synonyms: (R)-[1-(4-bromobenzenesulfonyl)pyrrolidin-2-yl]methanol
CAS NO:936727-80-9
Molecular Formula:
Molecular Weight: 320.207
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: (R)-[1-(4-bromobenzenesulfonyl)pyrrolidin-2-yl]methanol(CAS DataBase Reference)
NIST Chemistry Reference: (R)-[1-(4-bromobenzenesulfonyl)pyrrolidin-2-yl]methanol(936727-80-9)
EPA Substance Registry System: (R)-[1-(4-bromobenzenesulfonyl)pyrrolidin-2-yl]methanol(936727-80-9)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 936727-80-9(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 936727-80-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,3,6,7,2 and 7 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 936727-80:
(8*9)+(7*3)+(6*6)+(5*7)+(4*2)+(3*7)+(2*8)+(1*0)=209
209 % 10 = 9
So 936727-80-9 is a valid CAS Registry Number.

936727-80-9Upstream product

936727-80-9Downstream Products

936727-80-9Relevant academic research and scientific papers

Compositions for Treatment of Cystic Fibrosis and Other Chronic Diseases

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Paragraph 1157, (2015/09/22)

The present invention relates to pharmaceutical compositions comprising an inhibitor of epithelial sodium channel activity in combination with at least one ABC Transporter modulator compound of Formula A, Formula B, Formula C, or Formula D. The invention also relates to pharmaceutical formulations thereof, and to methods of using such compositions in the treatment of CFTR mediated diseases, particularly cystic fibrosis using the pharmaceutical combination compositions.

COMPOSITIONS FOR TREATMENT OF CYSTIC FIBROSIS AND OTHER CHRONIC DISEASES

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, (2012/04/23)

Modulators of ATP-binding cassette transporters

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Page/Page column 389, (2008/06/13)

Compounds of the present invention and pharmaceutically acceptable compositions thereof, are useful as modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator (“CFTR”). The present invention also relates to methods of treating ABC transporter mediated diseases using compounds of the present invention.

HETEROCYCLIC MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS

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Page/Page column 154, (2008/06/13)

Compounds of the present invention, and pharmaceutically acceptable compositions thereof, are useful as modulators of ATP-Binding Cassette ("ABC") transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator ("CFTR"). T

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