93680-04-7Relevant academic research and scientific papers
NOVEL SYNTHESIS OF 3-(N-SUBSTITUTED AMINO)-1-ISOINDOLENONES FROM 2-CYANOBENZALDEHYDE WITH AMINES
Sato, Ryu,Senzaki, Toshihide,Goto, Takehiko,Saito, Minoru
, p. 1599 - 1602 (1984)
Various 3-(N-substituted amino)-1-isoindolenones were readily synthesized quantitatively by reactions of 2-cyanobenzaldehyde with amines at low temperature such as 20 deg C.
Quick and easy access to N-Mannich bases of 1-isoindolinones by catalytic electroactivation of primary and secondary amines and tandem reaction with 2-formylbenzonitriles
Palombi, Laura,Di Mola, Antonia,Massa, Antonio
supporting information, p. 81 - 84 (2015/02/19)
N-Mannich bases of 1-isoindolinones can be rapidly assembled by reacting 2-formylbenzonitriles with electroactivated amines on a Pt cathode, using a catalytic amount of electricity. Usefully, chiral amines allow the attainment of enantiopure N-Mannich bases by simple chromatographic separation.
