936823-06-2Relevant articles and documents
A Highly Selective Palladium-Catalyzed Aerobic Oxidative Aniline-Aniline Cross-Coupling Reaction
Matsumoto, Kenji,Takeda, Satoshi,Hirokane, Tsukasa,Yoshida, Masahiro
, p. 7279 - 7283 (2019)
The first catalytic oxidative aniline-aniline cross-coupling reaction using oxygen as the terminal oxidant is reported. Anilines possessing a pyrrolidino group can be preferentially oxidized under mild aerobic conditions and reacted with other anilines to afford a variety of nonsymmetrical 2-aminobiphenyls with high selectivities. A heterogeneous palladium catalyst is used for the dehydrogenative cross-coupling of anilines with structurally diverse arenes. This reaction does not require stoichiometric oxidants and is an economical and environmentally friendly method.
N-heterocyclization of primary amines with dihalides using microreactors
He, Hongjie,Lin, Qi,Liu, Xiaofeng,Yang, Yongtai,Zhou, Yaming,Jia, Yu,Gao, Xiang
experimental part, p. 2512 - 2525 (2012/07/14)
(Chemical Equation Presented) A practical, rapid, and efficient reaction using microreactors for the direct N-alkylation from aniline derivatives and alkyl dihalides has been achieved in the presence of aqueous potassium carbonate at an elevated temperature. This improved synthetic methodology provides a straightforward microfluid approach to the synthesis of a variety of N-aryl azacycloalkanes. Copyright Taylor & Francis Group, LLC.
