93684-44-7

Basic information

• Product Name: Oxazole, 4,5-dihydro-4-(1-methylethyl)-2-(2-phenylethyl)-, (S)-
• CAS NO: 93684-44-7
• Molecular Formula: C14H19NO
• Molecular Weight: 217.311
• Mol File: 93684-44-7.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Oxazole, 4,5-dihydro-4-(1-methylethyl)-2-(2-phenylethyl)-, (S)-(CAS DataBase Reference)
• NIST Chemistry Reference: Oxazole, 4,5-dihydro-4-(1-methylethyl)-2-(2-phenylethyl)-, (S)-(93684-44-7)
• EPA Substance Registry System: Oxazole, 4,5-dihydro-4-(1-methylethyl)-2-(2-phenylethyl)-, (S)-(93684-44-7)

Safety Data

• Hazardous Substances Data: 93684-44-7(Hazardous Substances Data)

Upstream product

• 438496-21-0 (S)-N-(1-hydroxy-3-methylbutan-2-yl)-3-phenylpropanamide 
• 2026-48-4 (S)-valinol 
• 103-25-3 3-phenylpropanoic acid methyl ester 
• 501-52-0 3-Phenylpropionic acid 

Downstream Products

• 93684-54-9 4,5-dihydro-4-(1-methylethyl)-2-(2-phenylethyl)-3-(2-propenyl)oxazolinium 4-methylbenzenesulfonate 

Relevant articles and documents

CONDENSATION REACTION BY METAL CATALYST

The invention relates to a method for producing an azoline compound represented by the general formula (3): wherein R1 represents an optionally substituted hydrocarbon group, an optionally substituted alkoxy group, an optionally substituted alkoxycarbonyl group, a halogen atom, a substituted amino group, a substituted carbamoyl group or an optionally substituted heterocyclic group; R3, R4, R5 and R6 may be the same or different and each represents a hydrogen atom, an optionally substituted hydrocarbon group, an optionally substituted alkoxy group, an optionally substituted alkoxycarbonyl group, a halogen atom, a substituted amino group, a substituted carbamoyl group or an optionally substituted heterocyclic group; two arbitrary groups selected from R3, R4, R5 and R6 may bond to each other to form a ring; and Z1 represents an oxygen atom, a sulfur atom or a selenium atom; comprising reacting a carboxylic acid or a carboxylic acid derivative represented by the general formula (1): ????????R1CO2R2?????(1) wherein R1 is as defined above; R2 represents a hydrogen atom, an optionally substituted alkyl group or an optionally substituted aryl group; and R1 and R2 may bond to each other to form a ring; with an aminochalcogenide represented by the general formula (2): wherein R3, R4, R5, R6 and Z1 are as defined above; in the presence of a compound containing a group 12 metal element in the periodic table.

Direct conversion of esters, lactones, and carboxylic acids to oxazolines catalyzed by a tetranuclear zinc cluster

The tetranuclear zinc cluster Zn4(OCOCF3) 6O catalyzes the direct conversion of esters, lactones, and carboxylic acids to oxazolines with remarkable chemoselectivity. The Royal Society of Chemistry 2006.