936855-91-3

Upstream product

• 106-38-7 para-bromotoluene 
• 2984-50-1 1,2-Epoxyoctane 
• 1391742-96-3 C₂₁H₃₅BO₂ 
• 5720-05-8 4-methylphenylboronic acid 
• 380481-66-3 5,5-dimethyl-2-(4-methylphenyl)-1,3,2-dioxaborinane 

Downstream Products

• 936855-76-4 1-(4-methylphenyl)-2-octanone 
• 936855-81-1 1-diazo-1-(4-methylphenyl)-2-octanone 

Relevant academic research and scientific papers

Cu-Catalyzed cross-coupling reactions of epoxides with organoboron compounds

A copper-catalyzed cross-coupling reaction of epoxides with arylboronates is described. This reaction is not limited to aromatic epoxides, because aliphatic epoxides are also suitable substrates. In addition, N-sulfonyl aziridines can be successfully converted into the products. This reaction provides convenient access to β-phenethyl alcohols, which are valuable synthetic intermediates.

Rhodium-catalyzed intramolecular C-H insertion of α-aryl-α- diazo ketones

(Chemical Equation Presented) Direct diazo transfer proceeds smoothly with α-aryl ketones. The derived α-aryl-α-diazo ketones cyclize efficiently with Rh catalysis to give the corresponding α-aryl cyclopentanones.