937013-46-2Relevant articles and documents
Transition-metal-free method for the synthesis of benzo[b]thiophenes from o -halovinylbenzenes and K2S via direct SNAr-type reaction, cyclization, and dehydrogenation process
Zhang, Xiaoyun,Zeng, Weilan,Yang, Yuan,Huang, Hui,Liang, Yun
, p. 1687 - 1692 (2013)
A new, highly efficient procedure for the synthesis of benzothiophenes from easily available o-halovinylbenzenes and potassium sulfide has been developed. The reaction tolerated a wide range of functionalities, and various 2-substituted benzo[b]thiophenes
Discovery of SMP-304, a novel benzylpiperidine derivative with serotonin transporter inhibitory activity and 5-HT1Aweak partial agonistic activity showing the antidepressant-like effect
Yoshinaga, Hidefumi,Masumoto, Shuji,Koyama, Koji,Kinomura, Naoya,Matsumoto, Yuji,Kato, Taro,Baba, Satoko,Matsumoto, Kenji,Horisawa, Tomoko,Oki, Hitomi,Yabuuchi, Kazuki,Kodo, Toru
, p. 293 - 304 (2016/12/22)
We report the discovery of a novel benzylpiperidine derivative with serotonin transporter (SERT) inhibitory activity and 5-HT1Areceptor weak partial agonistic activity showing the antidepressant-like effect. The 3-methoxyphenyl group and the ph
