937018-50-3Relevant academic research and scientific papers
Synchronous photoinitiation of endothelial NO synthase activity by a nanotrigger targeted at its NADPH site
Beaumont, Edward,Lambry, Jean-Christophe,Gautier, Clement,Robin, Anne-Claire,Gmouh, Said,Berka, Vladimir,Tsai, Ah-Lim,Blanchard-Desce, Mireille,Slama-Schwok, Anny
, p. 2178 - 2186 (2008/02/04)
We designed a new nanotrigger to synchronize and monitor an enzymatic activity interacting specifically with the conserved NADPH binding site. The nanotrigger (NT) combines a docking moiety targeting the NADPH site and a chromophore moiety responsive to l
A NADPH substitute for selective photo-initiation of reductive bioprocesses via two-photon induced electron transfer
Robin, Anne-Claire,Gmouh, Said,Mongin, Olivier,Jouikov, Viatcheslav,Werts, Martinus H. V.,Gautier, Clement,Slama-Schwok, Anny,Blanchard-Desce, Mireille
, p. 1334 - 1336 (2008/01/01)
A NADPH substitute where the nicotinamide moiety is replaced by a chromophoric unit having much larger two-photon absorption cross-section and able to transfer electrons to flavins only upon excitation is described as an effective two-photon nanotrigger f
