937047-04-6

Basic information

• Product Name: 1-N-BOC-AMINO-4-BROMO-2-CYANO-1H-PYRROLE
• Synonyms: 1-N-BOC-AMINO-4-BROMO-2-CYANO-1H-PYRROLE;CarbaMic acid, N-(4-broMo-2-cyano-1H-pyrrol-1-yl)-, 1,1-diMethylethyl ester;tert-Butyl (4-bromo-2-cyano-1H-pyrrol-1-yl)carbamate
• CAS NO: 937047-04-6
• Molecular Formula: C10H12BrN3O2
• Molecular Weight: 286.12518
• Mol File: 937047-04-6.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1-N-BOC-AMINO-4-BROMO-2-CYANO-1H-PYRROLE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-N-BOC-AMINO-4-BROMO-2-CYANO-1H-PYRROLE(937047-04-6)
• EPA Substance Registry System: 1-N-BOC-AMINO-4-BROMO-2-CYANO-1H-PYRROLE(937047-04-6)

Safety Data

• Hazardous Substances Data: 937047-04-6(Hazardous Substances Data)

Usage

General Description

1-N-BOC-Amino-4-bromo-2-cyano-1H-pyrrole is a chemical compound with the molecular formula C11H13BrN2O2. It is a pyrrole derivative that contains a BOC-protected amino group, a bromine atom, and a cyano group. It is commonly used in organic synthesis as a building block for the preparation of various compounds, particularly in the pharmaceutical and agrochemical industries. The BOC-protected amino group provides a convenient handle for further functionalization and modification of the molecule. The presence of the bromine and cyano groups makes it a versatile starting material for the synthesis of a wide range of heterocyclic and bioactive compounds.

Upstream product

• 5176-27-2 N-tert-butyloxycarbonyl-pyrrole 
• 937046-95-2 N-(1H-pyrrol-1-yl)-carbamic acid tert-butyl ester 
• 870-46-2 t-butoxycarbonylhydrazine 
• 937046-96-3 tert-butyl (2-cyano-1H-pyrrol-1-yl)carbamate 

Downstream Products

• 937047-05-7 1-amino-4-bromo-1H-pyrrole-2-carbonitrile hydrochloride 
• 1201784-90-8 6-bromopyrrolo[2,1-f][1,2,4]triazine-2,4(1H,3H)-dione 

Relevant articles and documents

FGFR INHIBITOR AND MEDICAL APPLICATION THEREOF

Provided is a FGFR inhibitor, designating a compound represented by formula (I) or a pharmaceutically acceptable salt thereof. Also provided is the application of a drug for treating solid tumors, such as FGFR related diseases.

CDK kinase inhibitors

The invention discloses a compound with the general formula (I) and a salt thereof, wherein the compound can be taken as inhibitors of CDK kinase, particularly CDK4/6 kinase, and all variables are defined in the invention. The compound can be used for treating or preventing diseases such as cancer. The present application also relates to pharmaceutical compositions comprising the compound of formula (I).

PYRROLOTRIAZINE COMPOUNDS

A compound of formula (I), wherein all symbols have the same meanings as defined in the specification; a salt thereof, a solvate thereof, an N-oxide thereof, or a prodrug thereof, has a Btk inhibitory activity, and is useful as a method for preventing and