937047-47-7 Usage
General Description
5-Bromopyrrolo[1,2-f][1,2,4]triazin-4-amine, also known as BPTA, is a chemical compound that belongs to the class of pyrrolo-triazine derivatives. It is a heterocyclic compound containing both pyrrole and triazine rings, and its molecular formula is C7H5BrN6. BPTA has been studied for its potential pharmacological activities, particularly as an inhibitor of dihydrofolate reductase. This enzyme is a key target for cancer chemotherapy, and BPTA has shown promising activity as an antitumor agent in preclinical studies. Its unique structure and potential biological activities make BPTA an interesting compound for further investigation and potential therapeutic development.
Check Digit Verification of cas no
The CAS Registry Mumber 937047-47-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,3,7,0,4 and 7 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 937047-47:
(8*9)+(7*3)+(6*7)+(5*0)+(4*4)+(3*7)+(2*4)+(1*7)=187
187 % 10 = 7
So 937047-47-7 is a valid CAS Registry Number.
937047-47-7Relevant articles and documents
Regioselective mono-bromination of pyrrolo[2,1-f][1,2,4]triazin-4-amine
Bi, Lei,Fang, Sheng,Zhang, Ran,Yin, Xianzhen,Fu, Chenchao,Yao, Lei
, p. 7083 - 7084 (2015/02/19)
Pyrrolo[2,1-f][1,2,4]triazin-4-amine is regioselectively brominated when treated with 1,3-dibromo-5,5-dimethylimidazolidine-2,4-dione in different solvents. The brominated product, 5,7-dibromopyrrolo[2,1-f][1,2,4]triazin-4-amine predominates when the reaction is run in dichloromethane. The subsequent debromination process utilizes lithium-bromine exchange to give the desired product 5-bromo-pyrrolo[2,1- f][1,2,4]triazin-4-amine.