937058-20-3Relevant academic research and scientific papers
Palladium-catalyzed diastereoselective coupling of propargylic oxiranes with terminal alkynes
Yoshida, Masahiro,Hayashi, Maiko,Shishido, Kozo
, p. 1643 - 1646 (2008/02/02)
A diastereoselective coupling of propargylic oxiranes with terminal alkynes has been developed with use of a palladium catalyst. The stereochemistries of the resulting 4-alkynyl-substituted 2,3-allenols have been altered depending on the palladium catalyst. An optically active antf-substituted aliene was synthesized from the reaction of an enantiomerically enriched propargylic oxirane without loss of chirality.
