937172-16-2Relevant academic research and scientific papers
Structure-activity based study of the Smac-binding pocket within the BIR3 domain of XIAP
Wist, Aislyn D.,Gu, Lichuan,Riedl, Stefan J.,Shi, Yigong,McLendon, George L.
, p. 2935 - 2943 (2007)
A small series of peptide mimics was designed and synthesized to contain a heterocyclic ring in place of the potentially labile N-terminal peptide bond of the tetrapeptide containing the Smac-XIAP-binding motif. Two Smac mimics were shown to bind to the B
