93725-04-3Relevant articles and documents
Cycloaddition d'ylures d'azomethine derives de la 3,4-dihydro-6,7-dimethoxy-3-methoxycarbonyl-isoquinoleine
Lakhlifi, Tahar,Sedqui, Ahmed,Laude, Bernard,An, Nguyen Dinh,Vebrel, Joel
, p. 1156 - 1160 (2007/10/02)
Three azomethine ylide precursors including the 3,4-dihydro-6,7-dimethoxyisoquinoline-3-carboxylate moiety were synthesized.The 1,3-dipolar species formed from these products react with activated dipolarophilic olefines leading diastereospecifically to derivatives of 4',5'-dimethoxy-1,2-benzo-4,7-imino-4-methoxycarbonyl-1-cycloheptene.Proton magnetic resonance data allowed the determination of the stereochemistry of the cycloadducts. Key words: cyclic azomethine ylide, azabicyclic compounds, stereochemistry.