93733-74-5Relevant academic research and scientific papers
Inhibitors of the cysteine synthase CysM with antibacterial potency against dormant mycobacterium tuberculosis
Brunner, Katharina,Maric, Selma,Reshma, Rudraraju Srilakshmi,Almqvist, Helena,Seashore-Ludlow, Brinton,Gustavsson, Anna-Lena,Poyraz, ?mer,Yogeeswari, Perumal,Lundb?ck, Thomas,Vallin, Michaela,Sriram, Dharmarajan,Schnell, Robert,Schneider, Gunter
supporting information, p. 6848 - 6859 (2016/08/05)
Cysteine is an important amino acid in the redox defense of Mycobacterium tuberculosis, primarily as a building block of mycothiol. Genetic studies have implicated de novo cysteine biosynthesis in pathogen survival in infected macrophages, in particular f
