937364-80-2Relevant articles and documents
SAR studies on a novel series of human cytomegalovirus primase inhibitors
Chen,Adrian,Cushing,DiMaio,Liang,Mayorga,Miao,Peterson,Powers,Spector,Stein,Wright,Xu,Ye,Jaen
, p. 2188 - 2192 (2008/02/03)
A novel series of imidazolylpyrimidines were found to possess inhibitory activity against the human CMV UL70 primase. Extensive SAR studies on an HTS lead led to potent, orally bioavailable compounds with anti-CMV IC50 values of 150 nM in both