937369-86-3Relevant academic research and scientific papers
Process development for a novel pleuromutilin-derived antibiotic
Andemichael, Yemane,Chen, Jun,Clawson, Jacalyn S.,Dai, Wenning,Diederich, Ann,Downing, Susan V.,Freyer, Alan J.,Liu, Peng,Oh, Lynette M.,Patience, Daniel B.,Sharpe, Sonja,Sisko, Joseph,Tsui, Julie,Vogt, Julie,Wang, Jun,Wernersbach, Lori,Webb, Edward C.,Wertman, James,Zhou, Leon
scheme or table, p. 729 - 738 (2010/04/22)
A scalable synthesis of a novel pleuromutilin-based antibiotic is reported. The synthesis features the scale-up of an interesting skeletal rearrangement of the pleuromutilin core and isolation of a highly purified product despite starting with relatively
