937371-86-3

Basic information

• Product Name: (E)-acetophenone O-(4-methoxybenzyl) oxime
• Synonyms: (E)-acetophenone O-(4-methoxybenzyl) oxime
• CAS NO: 937371-86-3
• Molecular Weight: 255.316
• Mol File: 937371-86-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (E)-acetophenone O-(4-methoxybenzyl) oxime(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-acetophenone O-(4-methoxybenzyl) oxime(937371-86-3)
• EPA Substance Registry System: (E)-acetophenone O-(4-methoxybenzyl) oxime(937371-86-3)

Safety Data

• Hazardous Substances Data: 937371-86-3(Hazardous Substances Data)

Upstream product

• 10341-75-0 (E)-1-phenylethanone oxime 
• 824-94-2 p-methoxybenzyl chloride 
• 613-91-2 acetophenone oxime 

Downstream Products

• 2627-86-3 (S)-1-phenyl-ethylamine 
• 33290-12-9 (1S)-N-1-Phenethyl-3-hydroxy-2,2-dimethylpropanamide 

Relevant articles and documents

CATALYTIC ASYMMETRIC SYNTHESIS OF PRIMARY AMINES VIA BORANE REDUCTION OF OXIME ETHERS USING SPIROBORATE ESTERS

Asymmetric reduction of arylalkyl and pyridylalkyl ketoxime ether with borane catalyzed by several chiral spiroborates derived from non-racemic 1,2-amino alcohols are presented. Complete conversion of oxime to primary amine is highly dependant of the catalyst, source and amount of borane and temperature. The conversion and enantioselectivity is determined by the benzylic substitution of the oxime. After optimization, a catalyst derived from diphenyl valinol could, successfully, afford primary amines with good yield and enantioselectivity up to 99% ee. Using the developed methodology, other related non-racemic primary pyridyl alkyl methanamines were also prepared in high chemical yield and excellent enantioselectivity.

Regioisomeric 5(3)-aminomethyl-3(5)-phenylisoxazoles: Synthesis, spectroscopic discrimination, and muscarinic activity

The regioselective synthesis of isomeric 5(3)-aminomethyl-3(5)-phenyl isoxazoles using different methods is described. Spectroscopic data, especially mass spectrometric fragmentation, were used to identify and characterize the regioisomers. The muscarinic