937372-03-7

Usage

Uses

Used in Pharmaceutical Industry:
CarbaMic acid, N-(3,4-diaMinophenyl)-, 1,1-dimethylethyl ester is used as a chemical intermediate for the synthesis of various pharmaceutical compounds. Its unique structure and reactivity make it a valuable component in the development of new drugs.
Used in Dye Industry:
In the dye industry, CarbaMic acid, N-(3,4-diaMinophenyl)-, 1,1-dimethylethyl ester is used as a precursor in the production of dyes. Its chemical properties allow for the creation of a wide range of colors and hues, making it a versatile component in dye formulation.
Used in Medicinal Chemistry Research:
CarbaMic acid, N-(3,4-diaMinophenyl)-, 1,1-diMethylethyl ester is also utilized in medicinal chemistry research for the exploration of new drug candidates and the study of molecular interactions. Its presence in research settings aids in understanding the mechanisms of action and potential therapeutic applications of related compounds.

InChI:InChI=1S/C11H17N3O2/c1-11(2,3)16-10(15)14-7-4-5-8(12)9(13)6-7/h4-6H,12-13H2,1-3H3,(H,14,15)

Upstream product

• 219492-81-6 tert-butyl 4-amino-3-nitrophenylcarbamate 
• 5307-14-2 2-nitro-1,4-phenylenediamine 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 1377125-19-3 C₁₅H₁₈N₄O₃S 
• 1377128-73-8 C₁₅H₁₈N₄O₃S 

Relevant academic research and scientific papers

Mechanochemical catalytic transfer hydrogenation of aromatic nitro derivatives

Mechanochemical ball milling catalytic transfer hydrogenation (CTH) of aromatic nitro compounds using readily available and cheap ammonium formate as the hydrogen source is demonstrated as a simple, facile and clean approach for the synthesis of substituted anilines and selected pharmaceutically relevant compounds. The scope of mechanochemical CTH is broad, as the reduction conditions tolerate various functionalities, for example nitro, amino, hydroxy, carbonyl, amide, urea, amino acid and heterocyclic. The presented methodology was also successfully integrated with other types of chemical reactions previously carried out mechanochemically, such as amide bond formation by coupling amines with acyl chlorides or anhydrides and click-type coupling reactions between amines and iso(thio)cyanates. In this way, we showed that active pharmaceutical ingredients Procainamide and Paracetamol could be synthesized from the respective nitro-precursors on milligram and gram scale in excellent isolated yields.

An improved understanding of the reaction of bis(bromomethyl)quinoxaline 1-N-oxides with amines using substituent effects

(Chemical Equation Presented) The reaction of bis(bromomethyl)quinoxaline N-oxides with amines is interesting from a reaction mechanism perspective and due to the reported biological activity of compounds in this general class. The complex mechanism of th

Synthesis and chemical characterisation of target identification reagents based on an inhibitor of human cell invasion by the parasite Toxoplasma gondii

The use of phenotype-based screens as an approach for identifying novel small molecule tools is reliant on successful protein target identification strategies. Here we report on the synthesis and chemical characterisation of a novel reagent for protein ta

CARBONYLAMINO-BENZIMIDAZOLE DERIVATIVES AS ANDROGEN RECEPTOR MODULATORS

Compounds of structural formula (I) are modulators of the androgen receptor (AR) in a tissue selective manner. They are useful as agonists of the androgen receptor in bone and/or muscle tissue while antagonizing the AR in the prostate of a male patient or