937378-69-3Relevant academic research and scientific papers
Short and efficient synthesis of chiral furyl carbinols from carbohydrates
Boto, Alicia,Hernandez, Dacil,Hernandez, Rosendo
, p. 1721 - 1724 (2007)
Common sugar derivatives can be transformed in a few steps into chiral-substituted furyl carbinols. The mildness of the reaction conditions and the good yields obtained make this procedure an interesting alternative to the conventional processes.
Efficient conversion of carbohydrates into 1-C-alditols: Application to the synthesis of chiral γ-substituted butenolides and bicyclic alkaloid analogues
Boto, Alicia,Hernandez, Dacil,Hernandez, Rosendo
, p. 5287 - 5297 (2008/12/20)
(Chemical Equation Presented) Readily available sugar derivatives were transformed in a few steps into valuable, more complex products. The tandem radical scission of carbohydrates-oxidation reaction gave acetoxy acetals, which were converted into a variety of chiral C-alditols in good global yields and excellent 1,2-trans stereoselectivity. The reaction was the key step in the synthesis of hydroxylated γ-substituted butenolides and bicyclic alkaloid analogues.
