93744-08-2Relevant academic research and scientific papers
A FACILE ENANTIOSELECTIVE SYNTHESIS OF AN ARYLOXYPROPANOLAMINE β-BLOCKER THROUGH A TWO-STEP CONVERSION OF 1,3-DIOXOLANES INTO EPOXIDES
Nicola, Massimo,Depaoli, Adele,Inglesi, Marco
, p. 393 - 396 (2007/10/02)
A facile and convenient synthesis of the two enantiomers of P-0160, an aryloxypropanolamine β-blocker, is presented.The key step is the reaction of a chiral isopropylideneglycerol derivative with hydrobromic acid in acetic acid to afford a 2-acetoxy-1-bro
