93748-10-8

Upstream product

• 501-00-8 3-fluorophenylacetonitrile 
• 74-88-4 methyl iodide 

Downstream Products

• 93748-20-0 2-(3-fluorophenyl)-2-methylpropanoic acid 
• 1195173-50-2 1-(2-(3-fluorophenyl)propan-2-yl)-3-(4-(2-methylpyridin-4-yl)phenyl)urea 
• 1195179-16-8 2-(3-fluorophenyl)-2-methylpropanoyl azide 
• 1035261-89-2 diethyl 2-(2-(3-fluorophenyl)-2-methylpropanoyl)malonate 
• 1040860-88-5 2-(3-fluorophenyl)-2-methylpropanoic acid chloride 
• 1159010-38-4 2,2,2-trifluoro-N-1-[2-(3-fluoro-phenyl)-2-methyl-propyl]-acetamide 
• 160358-04-3 3-fluoro-β,β-dimethylphenethylamine 

Relevant academic research and scientific papers

NOVEL COMPOUNDS

The present invention relates to new CGRP-antagonists of general formula I wherein U, V, X, Y, R1, R2, R3 and R4 are defined as mentioned in the description, the tautomers thereof, the isomers thereof, the diastereomers thereof, the enantiomers thereof, the hydrates thereof, the mixtures thereof and the salts thereof as well as the hydrates of the salts, particularly the physiologically acceptable salts thereof with inorganic or organic acids or bases, medicaments containing these compounds, the use thereof and processes for the preparation thereof.

UREA COMPOUNDS AS GAMMA SECRETASE MODULATORS

The present invention provides compounds Formula (I) that are gamma secretase modulators and are therefore useful for the treatment of diseases treatable by modulation of gamma secretase such as Alzheimer's disease. Also provided are pharmaceutical compositions containing such compounds and processes for preparing such compounds.

NAPHTHALENONE COMPOUNDS EXHIBITING PROLYL HYDROXYLASE INHIBITORY ACTIVITY, COMPOSITIONS, AND USES THEREOF

Compounds of Formula (I) and Formula (II) are useful as inhibitors of HIF prolyl hydroxylases. Compounds of Formula(I) and Formula (II) have the following structures, where the definitions of the variables are provided herein.

Nonsteroidal antiinflammatory agents

The compound of formula 1 useful in the treatment of inflammation.