937595-70-5

Basic information

• Product Name: 5-Chloro-2-fluoropyridin-3-ylboronic acid
• Synonyms: Boronic acid, B-(5-chloro-2-fluoro-3-pyridinyl)-;5-Chloro-2-fluoropyridine-3-boronic acid;5-Chloro-2-fluoropyridine-3-boronic acid hydrate;5-Chloro-2-fluoropyridine-3-boronic Acid (contains varying amounts of Anhydride)
• CAS NO: 937595-70-5
• Molecular Formula: C₅H₄BClFNO₂
• Molecular Weight: 175.35
• Product Categories: blocks;BoronicAcids;Pyridines
• Mol File: 937595-70-5.mol
• Article Data: 0

Chemical Properties

• Melting Point: 125-126℃
• Boiling Point: 346.6 °C at 760 mmHg
• Flash Point: 163.4 °C
• Appearance: /
• Density: 1.51 g/cm³
• Vapor Pressure: 2.15E-05mmHg at 25°C
• Refractive Index: 1.533
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 5.70±0.58(Predicted)
• CAS DataBase Reference: 5-Chloro-2-fluoropyridin-3-ylboronic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Chloro-2-fluoropyridin-3-ylboronic acid(937595-70-5)
• EPA Substance Registry System: 5-Chloro-2-fluoropyridin-3-ylboronic acid(937595-70-5)

Safety Data

• Hazardous Substances Data: 937595-70-5(Hazardous Substances Data)

Usage

General Description

5-Chloro-2-fluoropyridin-3-ylboronic acid is a chemical compound with the molecular formula C5H4BClFNO2. It is a boronic acid derivative that contains a fluorine atom and a chlorine atom attached to a pyridine ring. 5-Chloro-2-fluoropyridin-3-ylboronic acid is commonly used in organic synthesis as a reagent for cross-coupling reactions, specifically in the construction of carbon-carbon and carbon-heteroatom bonds. It is an important building block in pharmaceutical and agrochemical research, and its unique structure and reactivity make it valuable in the development of new functional materials and biologically active compounds. Additionally, the presence of the boronic acid group in this compound allows for the formation of stable complexes with certain biomolecules, making it useful in chemical biology and medicinal chemistry research.

InChI:InChI=1/C5H4BClFNO2/c7-3-1-4(6(10)11)5(8)9-2-3/h1-2,10-11H

Downstream Products

• 1253573-75-9 4-(5-chloro-2-fluoropyridin-3-yl)-N,N-bis(4-methoxybenzyl)-6-methyl-1,3,5-triazin-2-amine 
• 1035266-51-3 3-{2-amino-4-[3-(5-chloro-2-fluoropyridin-3-yl)-4-fluorophenyl]-1-methyl-5-oxo-4,5-dihydro-1H-imidazol-4-yl}phenyl methanesulfonate