93764-91-1

Upstream product

• 695-34-1 2-Amino-4-methylpyridine 
• 7733-42-8 4-Nitro-α-chlor-α-isonitroso-acetophenon 
• 961-82-0 7-methyl-2-(4-nitrophenyl)imidazo[1,2-a]pyridine 

Relevant academic research and scientific papers

Catalyst-Free Regioselective C-3 Nitrosation of Imidazopyridines with tert -Butyl Nitrite under Neutral Conditions

We have successfully developed a novel and efficient catalyst-free method for the synthesis of 3-nitroso-substituted imidazopyridines, from readily available imidazo[1,2-a]pyridines and tert-butyl nitrite, in good to excellent yields. Importantly, the use

Convenient Synthesis of Fused Heterocycles from α-Ketohydroximoyl Chlorides and Heterocyclic Amines

Nitroso derivatives of imidazopyridine (11,13,14), imidazopyrimidine (15), imidazopyrazine (16), imidazopyrazole (17), and imidazo-1,2,4-triazole (19) were obtained in good yields from α-ketohydroximoyl chlorides 3 and 2-aminopyrazines (4-6), 2-aminopyrimidine (7), 2-aminopyrazine (8), 5-amino-3-phenylpyrazole (9), and 3-amino-2H-1,2,4-triazole (10), respectively.Under different conditions, the reaction of 3 with 3-amino-2H-1,2,4-triazole (10) and 2-aminopyrazine (8) afforded the noncyclized substitution products 18 and 22, respectively.The structures of the products were assigned and confirmed on the basis of their elemental analyses, spectral data, and alternate synthesis wherever possible.