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α,α-bis(4-fluorophenyl)-5-pyrimidinemethanol is a complex organic compound with the molecular formula C16H12F2N2O. It is characterized by a pyrimidine ring, which is a six-membered aromatic heterocyclic compound, and two 4-fluorophenyl groups attached to the alpha carbons of the pyrimidine ring. The presence of fluorine atoms in the phenyl groups imparts unique electronic and steric properties to the molecule. α,α-bis(4-fluorophenyl)-5-pyrimidinemethanol is of interest in medicinal chemistry and materials science due to its potential applications in the development of pharmaceuticals and as a building block for more complex molecules. Its structure allows for a range of chemical modifications and interactions, making it a versatile component in synthetic chemistry.

93765-57-2

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93765-57-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 93765-57-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,3,7,6 and 5 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 93765-57:
(7*9)+(6*3)+(5*7)+(4*6)+(3*5)+(2*5)+(1*7)=172
172 % 10 = 2
So 93765-57-2 is a valid CAS Registry Number.

93765-57-2Downstream Products

93765-57-2Relevant academic research and scientific papers

Biological evaluation of 5-substituted pyrimidine derivatives as inhibitors of brassinosteroid biosynthesis

Wang, Jing-Ming,Asami, Tadao,Yoshida, Shigeo,Murofushi, Noboru

, p. 817 - 822 (2007/10/03)

A series of 5-substituted pyrimidine derivatives was synthesized, and their ability to inhibit brassinosteroid biosynthesis was tested. The biological activity of these compounds was evaluated by the cress stem elongation method. Among the synthesized com

Aromatase Inhibition by 5-Substituted Pyrimidines and Dihydropirimidines

Taylor, Harold M.,Jones, C. David,Davenport, James D.,Hirsch, Kenneth S.,Kress, T.J.,Weaver, Dix

, p. 1359 - 1365 (2007/10/02)

The inhibition of estrogen biosynthesis has been suggested to be an effective treatment of hormone-dependent diseases, particularly breast cancer.Several series of 5-substituted pyrimidine derivatives have been synthesized and tested for their ability to inhibit the enzyme aromatase (estrogen synthetase).Compounds were evaluated in an in vitro assay that measured the inhibition of rat ovarian microsomal aromatase activity.Greatest inhibitory activity was achieved in the cases of diarylpyrimidinemethanols and diarylpyrimidinyl methanes which were substituted in the 4- and 4'-positions with electron-withdrawing substituents, particularly Cl.

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