93772-89-5Relevant academic research and scientific papers
Electron Impact Mass Spectrometry of Some 2,3-Dihydro-1-benzofuran-3-acetic Acids
Bravo, Pierfrancesco,Ticozzi, Calimero,Daolio, Sergio,Traldi, Pietro,Vecchi, Enrico
, p. 53 - 57 (1985)
The mass spectrometric behaviour of four 2,3-dihydro-1-benzofuran-3-acetic acids has been studied in detail with the aid of exact mass measurements, linked scans, collisionally activated decomposition, mass analysed ion kinetic energy spectra and labelling experiments.Unusual fragmentation pathways are emphasized for which mechanisms are proposed.
Synthesis and pharmacological characterization of a series of geometrically constrained 5-HT2A/2C receptor ligands
Chambers, James J.,Parrish, Jason C.,Jensen, Niels H.,Kurrasch-Orbaugh, Deborah M.,Marona-Lewicka, Danuta,Nichols, David E.
, p. 3526 - 3535 (2007/10/03)
In studies of the SAR of phenethylamine-type serotonin 5-HT2A receptor agonists, substituted conformationally constrained tetrahydronaphthofurans were designed to investigate the optimal conformation of the 2-aminoethyl moiety. These compounds
Substituted naphthofurans as hallucinogenic phenethylamine -Ergoline hybrid molecules with unexpected muscarinic antagonist activity
Monte, Aaron P.,Marona-Lewicka, Danuta,Lewis, Mechelle M.,Mailman, Richard B.,Wainscott, David B.,Nelson, David L.,Nichols, David E.
, p. 2134 - 2145 (2007/10/03)
A series of substituted racemic naphthofurans were synthesized as 'hybrid' molecules of the two major prototypical hallucinogenic drug classes, the phenethylamines and the tryptamines/ergolines. Although it was hypothesized that these new agents might pos
CNS affecting 5-oxy-3-aminomethyl-dihydro-benzofurans and benzothiophenes
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, (2008/06/13)
The present invention relates to 3-aminomethyl derivatives of indane, dihydrobenzofurane, dihydrobenzothiophene, and indoline, acid addition salts thereof, isomers thereof, methods of preparation, pharmaceutical compositions and method of treating CNS-disorders such as schizophrenia, Parkinson's disease, depression, anxiety, migraine and senile dementia, or in the cure of cardiovascular diseases, by administering such a derivative.
OXYGEN HETEROCYCLES BY SULPHUR YLIDE ANNULATION: 2,3-DIHYDRO-BENZOFURAN-3-ACETIC ACIDS FROM ortho-HYDROXYBENZALACETIC ACID METHYL ESTERS AND DIMETHYLSULPHOXONIUM METHYLIDE
Bravo, Pierfrancesco,Gentile, Anna,Ticozzi, Calimero
, p. 89 - 92 (2007/10/02)
Several 2,3-dihydro-benzofuran-3-acetic acids have been synthesized from ortho-hydroxybenzalacetic acid methyl esters and dimethylsulphoxonium methylide by an annulation reaction.
