937724-76-0 Usage
Description
1-BOC-3-(1-PIPERIDINYLCARBONYL)PIPERIDINE is a synthetic compound that is used in organic synthesis and medicinal chemistry. It is a piperidine derivative with a BOC (tert-butoxycarbonyl) protecting group on one nitrogen atom and a piperidinylcarbonyl group on another nitrogen atom. 1-BOC-3-(1-PIPERIDINYLCARBONYL)PIPERIDINE is known for its ability to modify the chemical structure of molecules and enhance their pharmacological properties.
Uses
Used in Organic Synthesis:
1-BOC-3-(1-PIPERIDINYLCARBONYL)PIPERIDINE is used as a building block for the synthesis of various organic molecules. Its unique structure allows for the creation of a wide range of compounds with different properties and applications.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 1-BOC-3-(1-PIPERIDINYLCARBONYL)PIPERIDINE is used as a key intermediate in the development of new drugs. Its ability to modify the chemical structure of molecules makes it a valuable tool for enhancing the pharmacological properties of potential drug candidates.
Used in Biological Research:
1-BOC-3-(1-PIPERIDINYLCARBONYL)PIPERIDINE is also used in the development of chemical probes for biological research. These probes can help scientists better understand the mechanisms of various biological processes and identify potential targets for drug discovery.
Check Digit Verification of cas no
The CAS Registry Mumber 937724-76-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,3,7,7,2 and 4 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 937724-76:
(8*9)+(7*3)+(6*7)+(5*7)+(4*2)+(3*4)+(2*7)+(1*6)=210
210 % 10 = 0
So 937724-76-0 is a valid CAS Registry Number.
InChI:InChI=1/C16H28N2O3/c1-16(2,3)21-15(20)18-11-7-8-13(12-18)14(19)17-9-5-4-6-10-17/h13H,4-12H2,1-3H3
937724-76-0Relevant articles and documents
Design and synthesis of a hybrid series of potent and selective agonists of α7 nicotinic acetylcholine receptor
Nencini, Arianna,Castaldo, Cristiana,Comery, Thomas A.,Dunlop, John,Genesio, Eva,Ghiron, Chiara,Haydar, Simon,Maccari, Laura,Micco, Iolanda,Turlizzi, Elisa,Zanaletti, Riccardo,Zhang, Jean
, p. 401 - 418 (2014/04/17)
α7 nicotinic acetylcholine receptor agonists are promising therapeutic candidates for the treatment of cognitive impairment. As a follow up of our internal medicinal chemistry program we investigated a novel series of α7 nAChR agonists. Starting from molecular docking studies on two series of molecules recently developed in our laboratories, an alternative scaffold was designed attempting to combine the optimal features of these previously identified urea and pyrazole compounds. Based on our previous SAR knowledge and on predicted drug-like properties, a small library was synthesized in parallel manner, affording compounds with excellent α7 nAChR activity, selectivity and preliminary ADME profile.
