937733-40-9Relevant academic research and scientific papers
Domino ring-opening/recyclization reactions of doubly activated cyclopropanes as a strategy for the synthesis of furoquinoline derivatives
Zhang, Zhiguo,Zhang, Qian,Sun, Shaoguang,Xiong, Tao,Liu, Qun
, p. 1726 - 1729 (2008/02/12)
(Chemical Equation Presented) In one easy step, doubly activated cyclopropanes 1 can be transformed into furoquinoline derivatives 2 through a tandem ring-opening/recyclization reaction mediated by SnCl4·5 H2O. A variety of substrates 1 derived from cheap starting materials were converted into the corresponding furoquinolines in good to excellent yields with high chemo- and regioselectivity. R = H, Me, OMe, Cl, or aromatic group is naphthyl.
