937738-85-7

Basic information

• Product Name: C₂₃H₂₉N₃O₂
• Synonyms: C₂₃H₂₉N₃O₂
• CAS NO: 937738-85-7
• Molecular Weight: 379.502
• Mol File: 937738-85-7.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: C₂₃H₂₉N₃O₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₃H₂₉N₃O₂(937738-85-7)
• EPA Substance Registry System: C₂₃H₂₉N₃O₂(937738-85-7)

Safety Data

• Hazardous Substances Data: 937738-85-7(Hazardous Substances Data)

Upstream product

• 13734-34-4 N-tert-butoxycarbonyl-L-phenylalanine 
• 1474-02-8 N-(1-benzyl-4-piperidinyl)-N-phenylpropionamide 
• 1155-56-2 1-benzyl-N-phenylpiperidin-4-amine 
• 1609-66-1 Norfentanyl 
• 1155-57-3 N-(1-benzylpiperidin-4-ylidene)aniline 
• 793-19-1 bis(2-methoxycarbonylethyl)benzylamine 
• 3612-20-2 1-phenylmethyl-4-piperidone 

Relevant articles and documents

Understanding the structural requirements of 4-anilidopiperidine analogues for biological activities at μ and δ opioid receptors

New 4-anilidopiperidine analogues in which the phenethyl group of fentanyl was replaced by several aromatic ring-contained amino acids (or acids) were synthesized to study the biological effect of the substituents on μ and δ opioid receptor interactions. These analogues showed broad (47 nM-76 μM) but selective (up to 17-fold) binding affinities at the μ opioid receptor over the δ opioid receptor, as predicted from the message-address concept.

Development of potent μ and δ opioid agonists with high lipophilicity

An SAR study on the Dmt-substituted enkephalin-like tetrapeptide with a N-phenyl-N-piperidin-4-ylpropionamide moiety at the C-terminal was performed and has resulted in highly potent ligands at μ and δ opioid receptors. In general, ligands with the substi