93779-35-2 Usage
Uses
Used in Pharmaceutical Industry:
(S)-AMINO-NAPHTHALEN-2-YL-ACETIC ACID is used as an anti-inflammatory agent for the treatment of pancreatitis, a condition characterized by inflammation of the pancreas. Its ability to inhibit proteases helps in reducing inflammation and alleviating symptoms associated with the disease.
(S)-AMINO-NAPHTHALEN-2-YL-ACETIC ACID is also used as an anticoagulant in the treatment of disseminated intravascular coagulation (DIC), a serious condition where blood clots form throughout the body, leading to multiple organ damage. By inhibiting the activity of blood coagulation factors, it helps prevent excessive clotting and reduces the risk of complications.
Used in Hemodialysis:
(S)-AMINO-NAPHTHALEN-2-YL-ACETIC ACID is used as a regional anticoagulant during hemodialysis, a procedure that helps remove waste products and excess fluids from the blood in patients with kidney failure. Its anticoagulant properties prevent blood clotting within the dialysis circuit, ensuring the smooth functioning of the process and reducing the risk of complications.
Used in COVID-19 Research:
(S)-AMINO-NAPHTHALEN-2-YL-ACETIC ACID is being studied for its potential to inhibit the entry of the SARS-CoV-2 virus into cells, making it a promising candidate for the treatment and prevention of COVID-19. Its ability to block viral entry could help in reducing the severity of the disease and limiting its spread.
Check Digit Verification of cas no
The CAS Registry Mumber 93779-35-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,3,7,7 and 9 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 93779-35:
(7*9)+(6*3)+(5*7)+(4*7)+(3*9)+(2*3)+(1*5)=182
182 % 10 = 2
So 93779-35-2 is a valid CAS Registry Number.
InChI:InChI=1/C12H11NO2/c13-11(12(14)15)10-6-5-8-3-1-2-4-9(8)7-10/h1-7,11H,13H2,(H,14,15)/t11-/m0/s1
93779-35-2Relevant academic research and scientific papers
Enzymatic conversion of unnatural amino acids by yeast D-amino acid oxidase
Caligiuri, Antonio,D'Arrigo, Paola,Rosini, Elena,Tessaro, Davide,Molla, Gianluca,Servi, Stefano,Pollegioni, Loredano
, p. 2183 - 2190 (2007/10/03)
Unnatural amino acids, particularly synthetic α-amino acids, are becoming crucial tools for modern drug discovery research. In particular, this application requires enantiomerically pure isomers. In this work we report on the resolution of racemic mixtures of the amino acids D,L-naphthylalanine and D,L-naphthylglycine by using a natural enzyme, D-amino acid oxidase from the yeast Rhodotorula gracilis. A significant improvement of the bioconversion is obtained using a single-point mutant enzyme designed by a rational approach. With this D-amino acid oxidase variant the complete resolution of all the unnatural amino acids tested was obtained: in this case, the bioconversion requires a shorter time and a lower amount of biocatalyst compared to the wild-type enzyme. The simultaneous production of the corresponding α-keto acid, a possible precursor of the amino acid in the L-form, improves the significance of the procedure.
Effects of extended aryl-substituted bisoxazoline ligands in asymmetric synthesis - Efficient synthesis and application of 4,4′-bis(1-naphthyl)-, 4,4′-bis(2-naphthyl)- and 4,4′-bis(9-anthryl)-2,2′- isopropylidenebis(1,3-oxazolines)
Van Lingen, Hester L.,Van Delft, Floris L.,Storcken, Roy P. M.,Hekking, Koen F. W.,Klaassen, Anouk,Smits, Jan J. M.,Ruskowska, Patrycja,Frelek, Jadwiga,Rutjes, Floris P. J. T.
, p. 4975 - 4987 (2007/10/03)
The steric influence of extended aryl substituents on 2,2′-bis(1,3- oxazollne) ligands was investigated in a series of asymmetric catalytic reactions such as Mukaiyama aldol and Michael reactions, hetero-Diels-Alder processes, and allylic alkylation react
