93780-80-4 Usage
Uses
Used in Pharmaceutical Industry:
Isorosmanol is used as a therapeutic agent for treating hyperpigmentation, a skin condition characterized by the overproduction of melanin. Its acetylcholinesterase inhibitory activity helps regulate melanin synthesis and distribution, leading to a more even skin tone and improved skin appearance.
Used in Cosmetic Industry:
Isorosmanol is used as an active ingredient in skincare products for its skin-lightening and brightening effects. It can be incorporated into creams, serums, and other formulations to help reduce the appearance of age spots, dark spots, and uneven skin tone, providing a more radiant and youthful complexion.
Used in Neurological Applications:
Isorosmanol's acetylcholinesterase inhibitory activity also makes it a potential candidate for the treatment of neurological disorders associated with cognitive decline, such as Alzheimer's disease. By inhibiting the enzyme acetylcholinesterase, Isorosmanol can help increase the levels of the neurotransmitter acetylcholine in the brain, which is crucial for memory and cognitive function.
Cytotoxicity
IC50 (μg/mL): 98 (HL-60), 100 (K562), 47(Hep G2), 58 (MCF-7), 121 (MOLT-4)(Farimani et al. 2012).IC50 (μg/mL): 6.58 (A2780), 7.97(SW1573), >34.64 (WiDr), >34.64(T-47D), 5.89 (HBL-100) (Guerreroet al. 2006), IC50 (μg/mL): 4 (P388)(Aoyagi et al. 2006)
Check Digit Verification of cas no
The CAS Registry Mumber 93780-80-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,3,7,8 and 0 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 93780-80:
(7*9)+(6*3)+(5*7)+(4*8)+(3*0)+(2*8)+(1*0)=164
164 % 10 = 4
So 93780-80-4 is a valid CAS Registry Number.
