937801-59-7Relevant academic research and scientific papers
Control of phosphoryl migratory transesterifications allows regioselecive access to sugar phosphates
Patel, Mitul K.,Davis, Benjamin G.
, p. 346 - 349 (2013)
Phosphate esters in polyhydroxylated systems are normally blighted by uncontrolled migration under a variety of reaction conditions. Cesium fluoride is demonstrated as a reagent to control migration of primary phosphates during transesterifications. This allows easy exchange of phosphoryl protecting groups enabling enhanced synthetic strategic flexibility and regioselective phosphate installation. Mechanistic analysis suggests that a fluoride-induced extended solvent sphere modulates steric bulk at phosphorus to favor the primary position.
Theoretical and experimental studies on methyl α-d-glucopyranoside derivatives
Che?mecka,Pasterny,Gawlik-Jedrysiak,Szeja,Wrzalik
, p. 498 - 507 (2007/10/03)
Theoretical quantum mechanical calculations using density functional theory (DFT) at the B3LYP level have been carried out for synthesized esterified methyl α-d-glucopyranoside derivatives. The predicted NMR characteristics obtained with GIAO method are c
