93788-76-2Relevant academic research and scientific papers
Synthesis and Ring Fissions of 4H-1,2,4-Oxadiazin-6(5H)-ones
Ajzert, K. Ilona,Takacs, Kalman
, p. 2999 - 3003 (2007/10/02)
Synthesis of 4H-1,2,4-oxadiazin-6(5H)-ones 4, comprising a new type of this class of compounds, has been carried out from 4-(ethoxycarbonylmethyl)-Δ2-1,2,4-oxadiazolin-5-ones 2 by alkaline hydrolysis and subsequent cyclisation of the amidoxime derivatives 3.The lactone ring of compound 4 is easily opened by hydrolysis and aminolysis, leading to the corresponding amide oxime derivatives 3 and 5.The reactions of 4 with nitrous acid gave the N-acylglycine derivatives 6.
