938022-22-1

Upstream product

• 149894-28-0 2-difluoroacetylcyclohexanone 

Downstream Products

• 1092459-40-9 1-({4-[3-(difluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl]-2-fluorophenyl}methyl)-2-pyrrolidinone 
• 1092459-28-3 3-(difluoromethyl)-1-[4-(1-pyrrolidinylcarbonyl)phenyl]-4,5,6,7-tetrahydro-1H-indazole 

Relevant academic research and scientific papers

COMPOUNDS WHICH POTENTIATE AMPA RECEPTOR AND USES THEREOF IN MEDICINE

Compound of formula (I) and salts thereof are provided: wherein A, R1, R, R2 are as defined in the specification. Processes for preparation, pharmaceutical compositions, and uses thereof as a medicament, for example in the treatment of a disease or condition mediated by a reduction or imbalance in glutamate receptor function, such as schizophrenia or cognition impairment, are also disclosed.

COMPOUNDS WHICH POTENTIATE AMPA RECEPTOR AND USES THEROF IN MEDICINE

Compound of formula (I) and salts thereof are provided: wherein X, Y, Z, R1, R2 and R3 are as defined in the specification. Processes for preparation, pharmaceutical compositions, and uses thereof as a medicament, for example in the treatment of a disease or condition mediated by a reduction or imbalance in glutamate receptor function, such as schizophrenia or cognition impairment, are also disclosed.