938162-99-3Relevant academic research and scientific papers
One-Pot Synthesis of 4-Heteroaryl-Substituted Pyrazoles: A Gold-Catalyzed Oxidation/1,2-Heteroaryl Migration Cascade Constitutes the Key Step
Yao, Xinbo,Wang, Tao,Zhang, Xi,Wang, Ping,Zhang, Bing,Wei, Junfa,Zhang, Zunting
, p. 1534 - 1539 (2016)
An efficient gold-catalyzed oxidation/1,2- heteroaryl migration cascade leading to 2-heteroaryl-substituted 1,3-diketones and its further application in the one-pot synthesis of 4-heteroaryl-substituted pyrazoles and the preparation of 4-heteroaryl-substituted isoxazoles are reported. A wide variety of 4-heteroaryl-substituted pyrazoles were obtained, indicating the broad substrate scope and functional group tolerance of this method.
