93818-23-6

Basic information

• Product Name: α-<2-Methoxycarbonyl-anilino>-phenylessigsaeure-methylester
• CAS NO: 93818-23-6
• Molecular Weight: 299.326
• Mol File: 93818-23-6.mol

Chemical Properties

• CAS DataBase Reference: α-<2-Methoxycarbonyl-anilino>-phenylessigsaeure-methylester(CAS DataBase Reference)
• NIST Chemistry Reference: α-<2-Methoxycarbonyl-anilino>-phenylessigsaeure-methylester(93818-23-6)
• EPA Substance Registry System: α-<2-Methoxycarbonyl-anilino>-phenylessigsaeure-methylester(93818-23-6)

Safety Data

• Hazardous Substances Data: 93818-23-6(Hazardous Substances Data)

Upstream product

• 22979-35-7 Methyl phenyldiazoacetate 

Relevant articles and documents

Formal Carbene Insertion into C?O or C?N Bond: An Efficient Strategy for the Synthesis of 2-Substituted 2H-Chromene Derivatives from Chromene Acetals or Hemiaminal Ethers

We report the palladium/Br?nsted acid co-catalyzed formal insertion of carbene into the C?O or C?N bond of 2H-chromene acetals or hemiaminal ethers. This transformation was initiated by the Br?nsted acid-promoted cleavage of the C?O or C?N bond, followed by modification of the leaving alcohol or amino fragments with palladium carbenes, and reassembly of the modified fragments. A variety of C-2 functionalized 2H-chromene derivatives were obtained in moderate yield (43～75%) with good to excellent diastereoselectivities (up to >95:5 dr) under mild conditions. (Figure presented.).