938443-57-3Relevant academic research and scientific papers
Synthesis and SAR of highly selective MMP-13 inhibitors
Li, Jianchang,Rush III, Thomas S.,Li, Wei,DeVincentis, Dianne,Du, Xuemei,Hu, Yonghan,Thomason, Jennifer R.,Xiang, Jason S.,Skotnicki, Jerauld S.,Tam, Steve,Cunningham, Kristina M.,Chockalingam, Priya S.,Morris, Elisabeth A.,Levin, Jeremy I.
, p. 4961 - 4966 (2007/10/03)
The structure-based design and synthesis of a series of novel biphenyl sulfonamide carboxylic acids as potent MMP-13 inhibitors with selectivity over MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-14, Aggrecanase 1, and TACE are described.
