93845-72-8

Upstream product

• 70147-50-1 2,3-O-isopropylidene-D-erythro-apiofuranoside 
• 98-59-9 p-toluenesulfonyl chloride 
• 70147-50-1 3-C-hydroxymethyl-2,3-O-isopropylidene-β-D-erythrofuranoside 
• 91738-34-0 2-C-(hydroxymethyl)-2,3:5,6-di-O-isopropylidene-α-D-mannofuranose 
• 14131-84-1 2,3:5,6-di-O-isopropylidene-α-D-mannofuranose 

Downstream Products

• 71582-80-4 (-)-malyngolide 
• 93836-30-7 1,4-di-O-benzoyl-2,3-O-isopropylidene-3-C-methylerythritol 

Relevant academic research and scientific papers

Synthesis of 3-C-(hydroxymethyl)erythritol and 3-C-methylerythritol.

3-C-(Hydroxymethyl)erythritol was prepared from 3-C-(hydroxymethyl)-2,3-O-isopropylidene-D-erythro-tetrofuranose (4) by hydrolysis followed by reduction, or by reduction followed by hydrolysis. Monotosylation of 4, followed by reduction with lithium aluminum hydride and hydrolysis, afforded 3-C-methylerythritol.