93884-11-8

Basic information

• Product Name: ethyl 3-[(methylsulfonyl)amino]benzoate
• Synonyms: ethyl 3-[(methylsulfonyl)amino]benzoate
• CAS NO: 93884-11-8
• Molecular Formula: C₁₀H₁₃NO₄S
• Molecular Weight: 243.27952
• Product Categories: Phenyls & Phenyl-Het;Phenyls & Phenyl-Het
• Mol File: 93884-11-8.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: ethyl 3-[(methylsulfonyl)amino]benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 3-[(methylsulfonyl)amino]benzoate(93884-11-8)
• EPA Substance Registry System: ethyl 3-[(methylsulfonyl)amino]benzoate(93884-11-8)

Safety Data

• Hazardous Substances Data: 93884-11-8(Hazardous Substances Data)

Upstream product

• 582-33-2 3-aminobenzoic acid ethyl ester 
• 124-63-0 methanesulfonyl chloride 

Downstream Products

• 1217088-68-0 C₁₀H₁₀N₂O₃S 
• 376347-09-0 N-(3-hydroxymethylphenyl)methanesulfonamide 
• 184896-92-2 3-methanesulfonylamino-benzoyl chloride 
• 119085-49-3 N-[2-Acetyl-4-(3,4-dimethoxy-phenyl)-1,2,3,4-tetrahydro-isoquinolin-7-yl]-methanesulfonamide 
• 119085-46-0 N-[2-(3,4-Dimethoxy-phenyl)-2-hydroxy-ethyl]-3-methanesulfonylamino-benzamide 
• 119085-48-2 N-[4-(3,4-Dimethoxy-phenyl)-1,2,3,4-tetrahydro-isoquinolin-7-yl]-methanesulfonamide 
• 119085-50-6 N-[2-Acetyl-4-(3,4-dihydroxy-phenyl)-1,2,3,4-tetrahydro-isoquinolin-7-yl]-methanesulfonamide 
• 119085-47-1 N-(3-{[2-(3,4-Dimethoxy-phenyl)-2-hydroxy-ethylamino]-methyl}-phenyl)-methanesulfonamide 
• 295311-37-4 ethyl 3-(N-methylmethanesulphonamido)benzoate 
• 28547-13-9 3-(methanesulfonamido)benzoic acid 

Relevant articles and documents

Palladium-catalyzed regiocontrolled domino synthesis of N-sulfonyl dihydrophenanthridines and dihydrodibenzo[c, e]azepines: Control over the formation of biaryl sultams in the intramolecular direct arylation

A palladium-catalyzed domino N-benzylation/intramolecular direct arylation involving sulfonanilides and 2-bromobenzyl bromides has been developed for the first time, providing a workable access to N-sulfonyl dihydrophenanthridines in good to excellent yields. Under the optimized conditions, the formation of 5,6-dihydrophenanthridines was largely controlled over the formation of biaryl sultams containing a seven member ring. The optimized condition was found extendable to the regiocontrolled domino formation of N-sulfonyl-6,7-dihydro-5H-dibenzo[c,e]azepines over the biaryl sultam formation. Using an appropriate substrate, a biaryl sultam has been obtained exclusively.

AMIDE DERIVATIVES

The invention concerns amide derivatives of Formula (Ia) wherein X is -NHCO- or -CONH-; m is 0-3; R1 is a group such as hydroxy, halogeno, trifluoromethyl, cyano, mercapto, nitro, amino, carboxy and carbamoyl; n is 0-2; R2 is a group