NERVE GROWTH FACTOR FROM MOUSESUBMAXILL ARY GLANDS, also known as Nerve Growth Factor-7S (NGF-7S), is a high molecular weight complex derived from the submandibular salivary gland of male mice. It is a dimer of 118-residue polypeptide chains linked non-covalently, containing three intramolecular disulphide bridges. NGF-7S is an α2β2γ2 complex, where β2-NGF is the active neurotrophin, and is linked to the dimers of the glandular kallikrein serine proteinases members, α-NGF and γ-NGF. It serves as the prototype of the neurotrophin growth factor family.
Used in Pharmaceutical Industry:
NERVE GROWTH FACTOR FROM MOUSESUBMAXILL ARY GLANDS is used as a therapeutic agent for inducing neuronal differentiation in various cell types, such as PC12 and dorsal root ganglia (DRG) obtained from chick embryos of either sex (Gallus gallus). This application is crucial for the treatment and regeneration of damaged neurons, promoting nerve growth and repair.
Used in Research Applications:
NERVE GROWTH FACTOR FROM MOUSESUBMAXILL ARY GLANDS is used as a research tool for studying the mechanisms of neuronal growth, development, and regeneration. It aids scientists in understanding the complex processes involved in nerve growth and can contribute to the development of new therapeutic strategies for neurological disorders.
Used in Pharmaceutical Industry:
NERVE GROWTH FACTOR FROM MOUSESUBMAXILL ARY GLANDS is used as a therapeutic agent for inducing neuronal differentiation in various cell types, such as PC12 and dorsal root ganglia (DRG) obtained from chick embryos of either sex (Gallus gallus). This application is crucial for the treatment and regeneration of damaged neurons, promoting nerve growth and repair.
Used in Research Applications:
NERVE GROWTH FACTOR FROM MOUSESUBMAXILL ARY GLANDS is used as a research tool for studying the mechanisms of neuronal growth, development, and regeneration. It aids scientists in understanding the complex processes involved in nerve growth and can contribute to the development of new therapeutic strategies for neurological disorders.
93928-24-6
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Basic information
- Product Name: NERVE GROWTH FACTOR FROM MOUSE*SUBMAXILL ARY GLANDS
- Synonyms: NERVE GROWTH FACTOR FROM MOUSE*SUBMAXILL ARY GLANDS;nerve growth factor-2.5s from murine submaxillary gland;nerve growth factor-7s from murine submaxillary gland;2.5S-NERVE GROWTH FACTOR, FROM MOUSE SUBMAXILLARY GLANDS;Nerve Growth Factor-β from murine submaxillary gland;Nerve Growth Factor-7S
- CAS NO:93928-24-6
- Molecular Formula:
- Molecular Weight: 0
- EINECS: N/A
- Product Categories: N/A
- Mol File: 93928-24-6.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: −20°C
- Solubility: N/A
- CAS DataBase Reference: NERVE GROWTH FACTOR FROM MOUSE*SUBMAXILL ARY GLANDS(CAS DataBase Reference)
- NIST Chemistry Reference: NERVE GROWTH FACTOR FROM MOUSE*SUBMAXILL ARY GLANDS(93928-24-6)
- EPA Substance Registry System: NERVE GROWTH FACTOR FROM MOUSE*SUBMAXILL ARY GLANDS(93928-24-6)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: 22-24/25
- WGK Germany: 3
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 93928-24-6(Hazardous Substances Data)
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93928-24-6 Usage
Biochem/physiol Actions
Nerve growth factor (NGF) is a neurotrophin, which facilitates the differentiation and survival of specific subtypes of neurons of central nervous system and peripheral nervous system. However, nerve growth factor-7S (NGF-7S) lacks any neurotrophic activity as most part of β-NGF subunit is buried within the NGF-7S complex.Check Digit Verification of cas no
The CAS Registry Mumber 93928-24-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,3,9,2 and 8 respectively; the second part has 2 digits, 2 and 4 respectively.Calculate Digit Verification of CAS Registry Number 93928-24:
(7*9)+(6*3)+(5*9)+(4*2)+(3*8)+(2*2)+(1*4)=166
166 % 10 = 6
So 93928-24-6 is a valid CAS Registry Number.
93928-24-6Upstream product
93928-24-6Downstream Products
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NERVE GROWTH FACTOR FROM MOUSE*SUBMAXILL ARY GLANDS
