939399-53-8

Basic information

• Product Name: benzyl 3,3-difluorocyclobutylcarbaMate
• Synonyms: benzyl 3,3-difluorocyclobutylcarbaMate;Benzyl 3,3-Difluorocyclobutylcarbamate(WXC01882)
• CAS NO: 939399-53-8
• Molecular Formula: C₁₂H₁₃F₂NO₂
• Molecular Weight: 241.2339264
• Mol File: 939399-53-8.mol

Chemical Properties

• Boiling Point: 350.5±42.0 °C(Predicted)
• Appearance: /
• Density: 1.25±0.1 g/cm3(Predicted)
• PKA: 10.47±0.40(Predicted)
• CAS DataBase Reference: benzyl 3,3-difluorocyclobutylcarbaMate(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl 3,3-difluorocyclobutylcarbaMate(939399-53-8)
• EPA Substance Registry System: benzyl 3,3-difluorocyclobutylcarbaMate(939399-53-8)

Safety Data

• Hazardous Substances Data: 939399-53-8(Hazardous Substances Data)

Upstream product

• 130369-36-7 N-(Benzyloxycarbonyl)-3-amino-1-cyclobutanone 
• 100-51-6 benzyl alcohol 

Downstream Products

• 637031-93-7 3,3-difluorocyclobutylamine hydrochloride 

Relevant articles and documents

Carbazole-Containing Sulfonamides as Cryptochrome Modulators

The subject matter herein is directed to carbazole-containing sulfonamide derivatives and pharmaceutically acceptable salts or hydrates thereof of structural formula I wherein the variable R1, R2, R3, R4, R5, R6, R7, A, B, C, D, E, F, G, H, a, and b are accordingly described. Also provided are pharmaceutical compositions comprising the compounds of formula I to treat a Cry-mediated disease or disorder, such as diabetes, obesity, metabolic syndrome, Cushing's syndrome, and glaucoma.

THERAPEUTICALLY ACTIVE COMPOSITIONS AND THEIR METHOD OF USE

Provided are methods of treating a cancer characterized by the presence of a mutant allele of IDH1 comprising administering to a subject in need thereof a compound described here.