939400-97-2Relevant academic research and scientific papers
Intramolecular fluorocyclizations of unsaturated carboxylic acids with a stable hypervalent fluoroiodane reagent
Geary, Gemma C.,Hope, Eric G.,Stuart, Alison M.
, p. 14911 - 14914 (2015)
A new class of fluorinated lactones was prepared by the intramolecular fluorocyclizations of unsaturated carboxylic acids by using the stable fluoroiodane reagent in combination with AgBF4. This unique reaction incorporates a cyclization, an aryl migration, and a fluorination all in one step. The fluoroiodane reagent, prepared easily from fluoride, can also be used without a metal catalyst to give moderate yields within just 1 hour, thus demonstrating that it is a suitable reagent for developing new 18F-labelled radiotracers for PET imaging. All in one: A new class of lactones containing a tertiary alkyl fluoride was prepared in high yields by using a stable fluoroiodane reagent. This unique reaction incorporates a cyclization, an aryl migration, and a fluorination all in one step.
Heck arylations of pent-4-enoates or allylmalonate using a palladium/tetraphosphine catalyst
Lemhadri, Mhamed,Battace, Ahmed,Zair, Touriya,Doucet, Henri,Santelli, Maurice
, p. 2270 - 2281 (2007/10/03)
The Heck reaction of aryl halides with functionalised alk-1-enes should be a powerful method for the synthesis of functionalised (E)-1-arylalk-1-ene derivatives. The major problem of this reaction is the palladium-catalysed migration of the carbon-carbon
Reagent-controlled stereoselective iodolactonizations
Haas, Juergen,Piguel, Sandrine,Wirth, Thomas
, p. 297 - 300 (2007/10/03)
Chemical equation presented Iodocyclizations are important transformations and among stereocontrolled iodocyclizations mostly substrate-controlled versions using a chiral auxiliary have been successfully investigated. This work reports on stereoselective
