939438-12-7

Basic information

• Product Name: (S)-tert-butyl 2-iodo-4-methoxy-3-(2-vinylcyclohex-2-enyloxy)benzyl(methyl)carbamate
• Synonyms: (S)-tert-butyl 2-iodo-4-methoxy-3-(2-vinylcyclohex-2-enyloxy)benzyl(methyl)carbamate
• CAS NO: 939438-12-7
• Molecular Weight: 499.389
• Mol File: 939438-12-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-tert-butyl 2-iodo-4-methoxy-3-(2-vinylcyclohex-2-enyloxy)benzyl(methyl)carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-tert-butyl 2-iodo-4-methoxy-3-(2-vinylcyclohex-2-enyloxy)benzyl(methyl)carbamate(939438-12-7)
• EPA Substance Registry System: (S)-tert-butyl 2-iodo-4-methoxy-3-(2-vinylcyclohex-2-enyloxy)benzyl(methyl)carbamate(939438-12-7)

Safety Data

• Hazardous Substances Data: 939438-12-7(Hazardous Substances Data)

Upstream product

• 1577-22-6 5-hexenoic acid 
• 138490-94-5 2-iodoisovanillin 
• 122334-35-4 N-methoxy-N-methyl-hex-5-enamide 
• 939438-02-5 tert-butyl 3-hydroxy-2-iodo-4-methoxybenzyl(methyl)carbamate 
• 939438-10-5 (S)-tert-butyl 2-iodo-4-methoxy-3-(1-(trimethylsilyl)oct-7-en-1-yn-3-yloxy)benzyl(methyl)carbamate 
• 939438-09-2 (R)-1-(trimethylsilyl)oct-7-en-1-yn-3-ol 
• 939438-17-2 1-(trimethylsilyl)oct-7-en-1-yn-3-one 
• 939438-11-6 (S)-tert-butyl 2-iodo-4-methoxy-3-(oct-7-en-1-yn-3-yloxy)benzyl(methyl)carbamate 

Downstream Products

• 939438-13-8 (S)-tert-butyl 3-(2-(2-hydroxyethyl)cyclohex-2-enyloxy)-2-iodo-4-methoxybenzyl(methyl)carbamate 

Relevant articles and documents

Stereocontrolled synthesis of (-)-galanthamine

An enantiosetective synthesis of (-)-galanthamine has been realized in 11 linear steps starting from isovanillin. A Mitsunobu aryl ether forming reaction was used to assemble the galanthamine backbone, which was stitched together using enyne ring-closing metathesis, Heck, and N-alkylatton reactions affording the tetracyclic ring system. Control of relative and absolute stereochemistry was derived from an easily accessible enantiomerically enriched propargylic alcohol 13.