939441-70-0Relevant academic research and scientific papers
A potent and orally efficacious, hydroxyethylamine-based inhibitor of β-Secretase
Kaller, Matthew R.,Harried, Scott S.,Albrecht, Brian,Amarante, Patricia,Babu-Khan, Safura,Bartberger, Michael D.,Brown, James,Brown, Ryan,Chen, Kui,Cheng, Yuan,Citron, Martin,Croghan, Michael D.,Graceffa, Russell,Hickman, Dean,Judd, Ted,Kriemen, Chuck,La, Daniel,Li, Vivian,Lopez, Patricia,Luo, Yi,Masse, Craig,Monenschein, Holger,Nguyen, Thomas,Pennington, Lewis D.,Miguel, Tisha San,Sickmier, E. Allen,Wahl, Robert C.,Weiss, Matthew M.,Wen, Paul H.,Williamson, Toni,Wood, Stephen,Xue, May,Yang, Bryant,Zhang, Jianhua,Patel, Vinod,Zhong, Wenge,Hitchcock, Stephen
, p. 886 - 891 (2013/01/15)
β-Secretase inhibitors are potentially disease-modifying treatments for Alzheimer's disease. Previous efforts in our laboratory have resulted in hydroxyethylamine-derived inhibitors such as 1 with low nanomolar potency against β-site amyloid precursor pro
