93953-39-0Relevant academic research and scientific papers
SYNTHETIC STUDIES ON NOGALAMYCIN CONGENERS ; SYNTHESES AND ANTITUMOR ACTIVITY OF VARIOUS NOGALAMYCIN CONGENERS
Matsuda, Fuyuhiko,Kawasaki, Motoji,Ohsaki, Masako,Yamada, Kaoru,Terashima, Shiro
, p. 5745 - 5760 (2007/10/02)
Various structural types of nogalamycin congeners and their partial structures, which had been previously synthesized in the course of our synthetic studies on the total syntheses or were originally produced by employing the explored synthetic scheme, were subjected to in vitro cytotoxicity and in vivo antitumor activity assay against P388 murine leukemia.These studies obviously disclosed novel aspects of the structure-activity relationships of nogalamycin congeners.
Synthesis of 8-Methoxy- and 8-Methoxy-6-methylhomophthalic Anhydrides, Key Intermediates for the Synthesis of Anthracyclinones and peri-Hydroxylated Polycyclic Aromatic Compounds
Tamura, Yasumitsu,Fukata, Fumio,Tsugoshi, Teruhisa,Sasho, Manabu,Nakajima, Yuko,Kita, Yasuyuki
, p. 3259 - 3262 (2007/10/02)
A novel synthesis of 8-methoxy- (1a) and 8-methoxy-6-methylhomophthalic anhydrides (1b) is described.Oxidative aromatization of methyl-2-(2-carbomethoxy-3-oxocyclohex-1-enyl)acetate (2) using 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ) or sublimed sul
