93970-93-5 Usage
Description
2'',4''-DIHYDROXY-3''-METHYLBUTYROPHENONE, also known as DMPB, is a chemical compound with the molecular formula C10H12O4. It is a derivative of phenylbutyric acid and possesses a unique structure that endows it with various functional properties. DMPB is characterized by its 2'',4''-dihydroxy and 3''-methylbutyryl groups, which contribute to its reactivity and potential applications in different industries.
Uses
Used in Organic Synthesis:
2'',4''-DIHYDROXY-3''-METHYLBUTYROPHENONE is used as a reagent in organic synthesis for its ability to participate in various chemical reactions, such as esterification, condensation, and substitution. Its functional groups allow it to act as a building block for the synthesis of more complex organic compounds.
Used in the Food Industry:
In the food industry, 2'',4''-DIHYDROXY-3''-METHYLBUTYROPHENONE is used as a flavoring agent due to its unique taste and aroma profile. Its ability to impart specific flavors to food products makes it a valuable ingredient in the development of new and innovative food formulations.
Used in Pharmaceutical Production:
2'',4''-DIHYDROXY-3''-METHYLBUTYROPHENONE is utilized in the production of pharmaceuticals due to its antimicrobial properties. Its ability to inhibit the growth of certain microorganisms makes it a potential candidate for the development of new antimicrobial drugs and treatments.
Used in Personal Care Products:
In the personal care industry, 2'',4''-DIHYDROXY-3''-METHYLBUTYROPHENONE is used in the formulation of various products, such as creams, lotions, and shampoos, due to its antimicrobial and preservative properties. Its ability to maintain the freshness and longevity of these products makes it a valuable ingredient in personal care formulations.
Used in the Development of New Materials and Bio-based Polymers:
2'',4''-DIHYDROXY-3''-METHYLBUTYROPHENONE has potential applications in the development of new materials and bio-based polymers due to its structural and functional properties. Its ability to participate in various chemical reactions and form stable linkages with other molecules makes it a promising candidate for the creation of innovative materials with diverse applications.
Check Digit Verification of cas no
The CAS Registry Mumber 93970-93-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,3,9,7 and 0 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 93970-93:
(7*9)+(6*3)+(5*9)+(4*7)+(3*0)+(2*9)+(1*3)=175
175 % 10 = 5
So 93970-93-5 is a valid CAS Registry Number.
InChI:InChI=1/C11H14O3/c1-3-4-10(13)8-5-6-9(12)7(2)11(8)14/h5-6,12,14H,3-4H2,1-2H3
93970-93-5Relevant articles and documents
Derivatives of Natural Product Agrimophol as Disruptors of Intrabacterial pH Homeostasis in Mycobacterium tuberculosis
Wu, Jie,Mu, Ran,Sun, Mingna,Zhao, Nan,Pan, Miaomiao,Li, Hongshuang,Dong, Yi,Sun, Zhaogang,Bai, Jie,Hu, Minwan,Nathan, Carl F.,Javid, Babak,Liu, Gang
, p. 1087 - 1104 (2019/05/22)
This article reports the rational medicinal chemistry of a natural product, agrimophol (1), as a new disruptor of intrabacterial pH (pHIB) homeostasis in Mycobacterium tuberculosis (Mtb). Through the systematic investigation of the structure-activity relationship of 1, scaffold-hopping of the diphenylmethane scaffold, pharmacophore displacement strategies, and studies of the structure-metabolism relationship, a new derivative 5a was achieved. Compound 5a showed 100-fold increased potency in the ability to reduce pHIB to pH 6.0 and similarly improved mycobactericidal activity compared with 1 against both Mycobacterium bovis-BCG and Mtb. Compound 5a possessed improved metabolic stability in human liver microsomes and hepatocytes, lower cytotoxicity, higher selectivity index, and similar pKa value to natural 1. This study introduces a novel scaffold to an old drug, resulting in improved mycobactericidal activity through decreasing pHIB, and may contribute to the critical search for new agents to overcome drug resistance and persistence in the treatment of tuberculosis.
ACETOPHENONE POTENTIATORS OF METABOTROPIC GLUTAMATE RECEPTORS
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Page 34-35, (2010/11/30)
The present invention is directed to compounds which are potentiators of metabotropic glutamate receptors, including the mGluR2 receptor, and which are useful in the treatment or prevention of neurological and psychiatric disorders associated with glutama
Allosteric potentiators of the metabotropic glutamate receptor 2 (mGlu2). Part 1: Identification and synthesis of phenyl-tetrazolyl acetophenones
Pinkerton, Anthony B.,Cube, Rowena V.,Hutchinson, John H.,Rowe, Blake A.,Schaffhauser, Hervé,Zhao, Xiumin,Daggett, Lorrie P.,Vernier, Jean-Michel
, p. 5329 - 5332 (2007/10/03)
We have identified and synthesized a series of aryl-tetrazoyl acetophenones as positive allosteric potentiators of the metabotropic glutamate receptor 2. Structure activity relationship studies directed toward improving the potency and level of potentiation led to the discovery of 22 (EC50 = 93 nM, 128% potentiation). We have identified and synthesized a series of aryl-tetrazoyl acetophenones as positive allosteric potentiators of the metabotropic glutamate receptor 2. Structure activity relationship studies directed toward improving the potency and level of potentiation led to the discovery of 22 (EC50 = 93 nM, 128% potentiation).
