93982-04-8

Basic information

• Product Name: 3-(bromomethyl)-6-(tert-butyl)-2,4-xylenol
• Synonyms: 3-(bromomethyl)-6-(tert-butyl)-2,4-xylenol;3-(Bromomethyl)-6-(1,1-dimethylethyl)-2,4-dimethylphenol;Phenol, 3-(broMoMethyl)-6-(1,1-diMethylethyl)-2,4-diMethyl-
• CAS NO: 93982-04-8
• Molecular Formula: C₁₃H₁₉BrO
• Molecular Weight: 271.19336
• EINECS: 301-193-7
• Mol File: 93982-04-8.mol

Chemical Properties

• Melting Point: 76-77 °C
• Boiling Point: 323.5±37.0 °C(Predicted)
• Appearance: /
• Density: 1.252±0.06 g/cm3(Predicted)
• Storage Temp.: Refrigerator
• Solubility: Chloroform, DCM, Ethyl Acetate
• PKA: 11.59±0.28(Predicted)
• CAS DataBase Reference: 3-(bromomethyl)-6-(tert-butyl)-2,4-xylenol(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(bromomethyl)-6-(tert-butyl)-2,4-xylenol(93982-04-8)
• EPA Substance Registry System: 3-(bromomethyl)-6-(tert-butyl)-2,4-xylenol(93982-04-8)

Safety Data

• Hazardous Substances Data: 93982-04-8(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
3-(bromomethyl)-6-(tert-butyl)-2,4-xylenol is used as an intermediate in the preparation of selective alpha-1 agonist and partial alpha-2 agonist topical decongestant. Its unique structure allows for the development of drugs that can effectively alleviate nasal congestion by targeting specific receptors in the nasal passages, providing relief without causing significant side effects.

Upstream product

• 109-87-5 Dimethoxymethane 
• 1879-09-0 2,4-dimethyl-6-tert-butylphenol 
• 50-00-0 formaldehyd 

Downstream Products

• 956582-17-5 6-tert-butyl-3-bromomethyl-2,4-dimethylphenyl acetate 
• 55699-10-0 2-(4-tert-butyl-3-hydroxy-2,6-dimethylphenyl)acetonitrile 
• 1262053-61-1 2-(4-tert-butyl-3-hydroxy-2,6-dimethylphenyl)aceto-⁽¹⁴⁾C-nitrile 
• 40601-76-1 1,3,5-tris(4-tert-butyl-3-hydroxy-2,6-dimethylbenzyl)isocyanurate 
• 956582-18-6 3-{(1H-benzo[d]imidazol-2-ylsulfanyl)methyl}-6-tert-butyl-2,4-dimethyl-phenyl acetate 

Relevant articles and documents

Synthesis of [2H4]oxymetazoline and [ 14C]oxymetazoline

An efficient synthesis of [2H4] and [ 14C]oxymetazoline has been developed. Both compounds follow the same synthetic route with the introduction of the label occurring at different synthetic steps. The synthesis of [2H4]oxymetazoline from [2H4]ethylene diamine was achieved in one step with a 40% yield. The synthesis of [14C]oxymetazoline from potassium [ 14C]cyanide was achieved in two steps with an overall radiochemical yield of 67%. Copyright

New chiral ligands from myrtenal and caryophyllene for asymmetric oxydation of sulfides catalyzed by metal complexes

From myrtenal and caryophyllene, widespread terpene compounds, three new chiral Schiff bases were prepared suitable for ligands in vanadium ions catalyzed sulfides oxidation to chiral sulfoxides.