94015-56-2Relevant academic research and scientific papers
Antiprotozoal agents
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, (2008/06/13)
Novel combinations of an antiprotozoal naphthoquinone and a 4-pyridinol or an alkanoic ester thereof wherein the antiprotozoal activity of the combination is potentiated with respect to the corresponding activity of the components of the combination. The combinations are especially useful for the treatment or porphylaxis of malaria.
Naphthoquinone derivatives
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, (2008/06/13)
Novel antiprotozoal naphthoquinones having the general formula STR1 (wherein either R1 is hydrogen and R2 is selected from C1-6 alkoxy, aralkoxy, C1-6 alkyl-C1-6 alkoxy, phenyl substituted by one or two groups selected from halogen and C1-6 alkyl, halogen and perhalo-C1-6 alkyl; or R1 and R2 are both C1-6 alkyl or phenyl; and n is 0 or 1) and salt thereof. The compounds of formula (I) are useful for the treatment or prophylaxis of protozoal diseases including malaria, theileriosis and coccidiosis. Various processes for preparing compounds of formula (I) are described.
