94017-64-8Relevant academic research and scientific papers
Combining Fluoroalkylation and Defluorination to Enable Formal [3 + 2 + 1] Heteroannulation by Using Visible-Light Photoredox Organocatalysis
Chu, Xue-Qiang,Xie, Ting,Li, Lin,Ge, Danhua,Shen, Zhi-Liang,Loh, Teck-Peng
, p. 2749 - 2752 (2018)
A metal-free, visible-light photoredox-catalyzed three-component [3 + 2 + 1] heteroannulation for accessing modular fluoroalkylated pyrimidines from readily available silyl enol ether, amidine, and fluoroalkyl halide is developed. This protocol distinguishes itself by broad functional group tolerance in a regioselective manner, which provides a complement to the existing methods for the construction of pharmaceutically and biologically active organofluorine compounds.
THE 1,3 OC SILYL REARRANGEMENT OF SILYL ENOL ETHER ANIONS - SYNTHESIS OF α-SILYL KETONES
Corey, E. J.,Ruecker, Christoph
, p. 4345 - 4348 (2007/10/02)
Silyl enol ethers with sterically hindered silyl groups are transformed into the corresponding α-silyl ketones by treatment with n-butyllithium/potassium tert-butylate.
