94019-86-0Relevant academic research and scientific papers
BICYCLIC DERIVATIVES AS SPHINGOSINE-1 -PHOSPHATE RECEPTORS MODULATORS
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Page/Page column 27; 28;, (2015/11/16)
The present invention relates to novel bicyclic derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of sphingosine-1-phosphate receptors.
1,2,4-OXADIAZOL DERIVATIVES, THEIR PHARMACEUTICAL COMPOSITIONS AND THEIR USE AS SPHINGOSINE 1-PHOSPHATE 1 RECEPTOR AGONISTS
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Page/Page column 47-48, (2010/12/31)
1,2,4-Oxadiazol derivatives represented by formula (I) useful as sphingosine 1-phosphate 1 (S1P1) receptor agonists, processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of various disorders mediated via S1P1 receptor are disclosed.
Molecular Design by Cycloaddition Reaction. Part 43. Cycloaddition Reactions of Silyl Enol Ethers of 2-Acetylfuran and -thiophene and Related Benzo Analogues
Sasaki, Tadashi,Ishibashi, Yukio,Ohno, Masatomi
, p. 1972 - 1997 (2007/10/02)
The title compounds (5, 6, 11, 12 and 13) underwent cycloaddition reactions with typical dienophiles followed by oxidative rearomatization.The reactions of (5) and (6) with heterodienophiles gave rather open-chain adducts via a zwitterionic interm
