94022-95-4

Usage

Uses

Used in Organic Synthesis:
1-(2-bromoethyl)-2-(trifluoromethyl)benzene is used as a chemical intermediate for the synthesis of various organic compounds. Its unique structure allows for versatile reactions and transformations, making it a valuable building block in the creation of complex organic molecules.
Used in Pharmaceutical Production:
In the pharmaceutical industry, 1-(2-bromoethyl)-2-(trifluoromethyl)benzene is used as an intermediate in the production of certain drugs. Its presence in the molecular structure can contribute to the drug's efficacy, stability, and pharmacokinetic properties.
Used in Agrochemicals:
1-(2-bromoethyl)-2-(trifluoromethyl)benzene is also utilized in the development of agrochemicals, such as pesticides and herbicides. Its chemical properties can enhance the effectiveness of these products and contribute to their overall performance in agricultural applications.
Used in Materials Science:
Due to its unique structure and properties, 1-(2-bromoethyl)-2-(trifluoromethyl)benzene has potential applications in the field of materials science. It may be used in the development of new materials with specific properties, such as high thermal stability, chemical resistance, or other desirable characteristics.
Used in Research:
1-(2-bromoethyl)-2-(trifluoromethyl)benzene is a valuable compound for research purposes, particularly in the fields of organic chemistry, medicinal chemistry, and materials science. Its unique structure and properties make it an interesting subject for studying reaction mechanisms, exploring new synthetic routes, and investigating potential applications in various industries.

InChI:InChI=1/C9H8BrF3/c10-6-5-7-3-1-2-4-8(7)9(11,12)13/h1-4H,5-6H2

Upstream product

• 94022-96-5 2-[2-(trifluoromethyl)phenyl]ethanol 

Downstream Products

• 1382354-22-4 2-{3-(2-trifluoromethylphenethoxy)phenylamino}benzamide 
• 1508310-74-4 5-nitro-1-(2-(trifluoromethyl)phenethyl)-1H-indole 
• 1508310-51-7 2-(4-(ethylsulfonyl)phenyl)-N-(1-(2-(trifluoromethyl)phenethyl)-1H-indol-5-yl)acetamide 
• 1508310-75-5 1-(2-(trifluoromethyl)phenethyl)-1H-indol-5-amine 

Relevant academic research and scientific papers

INHIBITORS OF CYTOSOLIC PHOSPHOLIPASE A2

This invention provides chemical inhibitors of the activity of various phospholipase enzymes, particularly cytosolic phospholipase A2 enzymes (cPLA2), more particularly including inhibitors of cytosolic phospholipase A2 alpha enzymes (cPLAα). In some embodiments, the inhibitors have the Formula I: wherein the constituent variables are as defined herein.

New prenylamine-analogues: investigations of their influence on calcium-dependent biological systems

Chemically, prenylamine belongs to the diphenylalkylamine class.Compounds of this class are calcium antagonists with broad spectrum of activities due to their influence on both extracellular and intracellular sites.In the present study the calcium antagonistic profile of a recently developed new series of prenylamine analogues has been investigated using different in vitro systems.The inhibiting concentrations for the most active compound are ca. 1.5 μM; several derivatives are inactive up to a concentration of 10 μM.Structural modifications towards an increase oflipophilicity make these molecules interact (inhibition) with the intracellular calcium-binding protein calmodulin; for the series no correlation between calcium-blocking and calmodulin antagonistic effects has been found. - Keywords: prenylamine derivatives /diphenylalkylamines /calcium antagonists / calmodulin antagonists / qualitative structure-activity relationship

Benzhydryl derivatives having calmodulin inhibitor properties

The invention relates to a benzhydryl derivative having the formula STR1 wherein each of the groups R1, R2, and R3 represents one to four substituents independently selected from the group consisting of hydrogen, lower alkyl, halogen, and CF3, and at least one of the groups R1, R2, and R3 is halogen or CF3 ; R4 represents hydrogen or methyl; n is 2, 3, or 4; m is 1, 2, or 3; and X represents O or S; or its pharmaceutically acceptable salts. The benzhydryl derivative of the invention can be used to treat patients who are suffering from diseases which are influenced by calmodulin.